Cognitive slowing in HIV infection: a sign of premature aging?

Authors

  • Félix Jesús Amador Romero Servicio de Fisiología, Instituto Nacional de Salud de los Trabajadores. alzada de Bejucal km 7 ½, Nº 3035, entre Heredia y 1ª, La Esperanza, Apartado 9064, CP 10 900, Arroyo Naranjo, La Habana, Cuba
  • Jorge Heliodoro Mayor Ríos

Keywords:

cognitive slowing, discriminative reaction time, aging, cognitive-motor disorder, HIV-1

Abstract

Introduction: The cognitive slowing is considered an early sign of cognitive motor disorder associated to HIV and natural aging, the best field where it has been described. However, there are no reports that establish a precise relationship between the effect of the virus and age on cognitive dynamic. Objective: To describe and identify similarities and differences in the dynamic pattern of cognitive slowing of these groups. Method: 48 asymptomatic HIV-positive, 35 healthy elder adults and 80 seronegative controls were compared with each other, during the execution of increasing difficulty and automated processing tasks, using a procedure of behavior splitting of the reaction time. Results: There is a similar cognitive slowing pattern in asymptomatic HIV-positive and elderly, characterized by the intervention of at least two factors, one of additive general slowing consisting of an exclusive reduction of speed and the other one, related to attentional control limitations during processing complexity. Conclusions: The similarity found suggests that the neurotropic virus action mimics the action of age on cognitive functioning, a fact that could be interpreted in terms of a "premature aging" of these functions. The implications of this result for public health are analyzed.

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Author Biographies

Félix Jesús Amador Romero, Servicio de Fisiología, Instituto Nacional de Salud de los Trabajadores. alzada de Bejucal km 7 ½, Nº 3035, entre Heredia y 1ª, La Esperanza, Apartado 9064, CP 10 900, Arroyo Naranjo, La Habana, Cuba

Licenciado en Psicología, Doctor en Ciencias de la Salud, Máster en Salud de los Trabajadores, Especialista en Psicología de la Salud, Investigador y Profesor Auxiliar

Jorge Heliodoro Mayor Ríos

Licenciado en Psicología, Doctor en Ciencias Psicológicas, Máster en Salud de los Trabajadores, Investigador y Profesor Titular

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Published

2020-04-19

How to Cite

1.
Amador Romero FJ, Mayor Ríos JH. Cognitive slowing in HIV infection: a sign of premature aging?. rev cuban salud trabajo [Internet]. 2020 Apr. 19 [cited 2025 Jun. 27];18(1):14-21. Available from: https://revsaludtrabajo.sld.cu/index.php/revsyt/article/view/2

Issue

Vol. 18 No. 1 (2017): (Enero - Abril)

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Original articles

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